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Description

The ability of this receptor to modulate intricate signaling pathways positions it as a critical player in maintaining metabolic homeostasis, particularly in patients with conditions such as obesity, diabetes, and cardiovascular diseases

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In recent years, numerous studies have focused on the role of GPER in PCOS, suggesting that GPER plays a significant role in the pathogenesis of this condition [154, 155]

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10.3389/fphar.2019.01197 88 LiH.GeH.SongX.TanX.XiongQ.GongY.et al (2023a)

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The Wnt and Notch signaling pathways are essential for preserving the quiescent-proliferative equilibrium of intestinal epithelial stem cells 29,30

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