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At the time of its discovery, the EPR effect was considered an Achilles heel of cancer, expected to enable efficient accumulation of nanomedicines at tumor sites and thereby improve oncology treatments 42

Ozempics SUSTAIN trials, although primarily focused on glycemic control, still demonstrated impressive weight loss averaging around 812%

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The ligatures on the CCA, ICA, and PPA were removed, but the ECA was permanently ligated above and below the opening

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