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72 NAC NAC is a cysteine prodrug and hepatic GSH precursor, and should be administered immediately as an antidote in patients with established APAP hepatotoxicity or those with high risk of developing this condition

Endocrine disruptors like BPA, phthalates, pesticides, and heavy metals pass through the liver

There was no significant difference in the incidence of adverse events and serious adverse events in patients with diabetic neuropathy who took 600 mg/day of lipoic acid for four years compared to those in the placebo group (78)

Previous studies have reported thresholded dose-response curves in oxidative DNA damage and attributed these observations to failed repair at the inflection point on the curve, thus allowing strand breaks to accumulate (Gagne et al., 2012