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Because APAP-induced liver injury typically manifests with pericentral necrosis surrounded by senescent hepatocytes, the damage does not occur equally throughout liver lobules, but the damaged site is surrounded by undamaged hepatocytes

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Acknowledgements This study is based in part on data from the Clinical Practice Research Datalink obtained under licence from the UK Medicines and Healthcare products Regulatory Agency

Florida Surgery and Weight Loss Center provides physician-guided medical weight loss and telehealth consultations for eligible patients, with treatment recommendations based on provider evaluation and clinical appropriateness