J Natl Cancer Inst 104(6):488492 Charron CS, Dawson HD, Albaugh GP, Solverson PM, Vinyard BT, Solano-Aguilar GI, Molokin A, Novotny JA (2015) A single meal containing raw, crushed garlic influences expression of immunity-and cancer-related genes in whole blood of humans
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It accumulates as unmetabolized folic acid (UMFA) and competes with active folates for receptors. Conversion between the two active forms is unreliable : it requires multiple enzymes (MTR, MTRR, SHMT, MTHFR, MTHFS) all working properly, and is easily blocked by low glutathione, B12 deficiency, heavy metals, or oxidative stress
Generally not associated with chronic liver damage, though foci of cellular alteration may occur in damaged liver
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