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Exendin-4 (exenatide) has been shown to be effective in a mouse model of ALD, ameliorating hepatic steatosis and improving metabolic markers such as insulin resistance and lipid levels

Special populations require additional consideration: Pregnancy and breastfeeding : Wegovy is contraindicated in pregnancy and should be discontinued at least two months before planned conception

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This site should be located approximately halfway between the shoulder and the elbow, on the outer back portion of the arm where there is sufficient subcutaneous fatty tissue

This is similar to the results reported for Mounjaro in the SURMOUNT-1 trial, where 36.2% of participants taking the highest (15mg) dose also lost at least 25% of their body weight