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Multiple sclerosis, an autoimmune demyelinating disease of the central nervous system, may benefit from the anti-inflammatory and neuroprotective properties of GLP-1RAs

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Thus, C57BL/6 mice were intraperitoneally (i.p.) injected with indomethacin (IND), a PTGS1/PTGS2 inhibitor, at a dose of 10 mg/kg of body weight or with the vehicle (DMSO) 24 h before challenge with HSV-1 (1 10 5 PFU), followed by treatment once a day, and serum and brain tissues were then extracted at 5 dpi (Fig

Three-year efficacy of complex insulin regimens in type 2 diabetes