What they did: Isolated human chondrocytes (from osteoarthritis patients and healthy donors) were exposed to AOD-9604 at doses 1 to 1000 nM
Wound Healing: It accelerates repair by stimulating the synthesis of collagen and other key extracellular matrix components, while also promoting angiogenesis (the formation of new blood vessels)
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The levels of individual vitamers in the investigated matrices, which were too low to be detected by the native SIDA method, became detectable by the highly sensitive LC-MS/MS after all cobalamins were enriched as CNCbl by cyanidation conversion
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