This activity is instrumental in safeguarding hippocampal neurons from the deleterious impacts of glutamate-induced excitotoxicity and hypoxic conditions
Zagazig Vet J
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Carnitine, Acylcarnitines and Fatty Acid Transport into Mitochondria The substrates for oxidation and most of the energy production in cells are unesterified fatty acids, which originate from three main sources: exogenous fatty acids that enter cells from the circulation, either from the diet or by mobilization from other tissues, those that arise via synthesis de novo from acetyl-CoA, and those released within the cell by the hydrolysis of phospholipids and triacylglycerols
Glutathione measurement Total hepatic glutathione (GSH) was measured in liver homogenates using the Glutathione Colorimetric Detection Kit (Invitrogen, Carlsbad, CA) per the manufacturers instructions