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Quantitative profiling using HPLC-MS/MS is highly reliable when employing an isotope dilution approach, wherein stable isotope-labeled internal standards (IS) effectively compensate for matrix effects (examples are shown for GSH and Glu in Fig

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Research interest in the AngIV/AT4 receptor system was further encouraged by the finding that AT1 and AT2 receptor antagonists failed to block learning and memory tasks in animal models [70]