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As of 2026: No Human Clinical Trials: There are no published, peer-reviewed human clinical trials investigating the combined administration of MOTS-c and Retatrutide

Funding This work was supported by the National Natural Science Foundation of China (grant numbers 82173424, 81974476, 81673065, 81830096, 81773341) and the Program of Introducing Talents of Discipline to Universities (111 Project, grant number B20017)

Total weight loss at 48 weeks in clinical trials averaged 24.2% at the highest Retatrutide dose

[DOI] [PMC free article] [PubMed] [Google Scholar] 80.Souza S.S., Castro F.A., Mendona H.C., Palma P.V.B., Morais F.R., Ferriani R.A., Voltarelli J.C

Additional Tests: a