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: 250-300

some patients achieve near-normal HbA1c levels Weight loss timeline: Weeks 14: Modest weight loss of 13 kg, primarily reflecting reduced caloric intake due to appetite suppression Months 23: More noticeable weight reduction of 35% of initial body weight Months 36: Continued steady weight loss

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Moreover, the IC50 values of MitoQ, DPI and vincristine are within the range observed for IMR-5/75 and Be(2)-C MNA cell lines ( Figures 2A, B