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Beyond its function in DNA repair, MTHFD2 interacts with CDK2 to enhance Rb phosphorylation, triggering the release and activation of E2F1 (Fig

These cells secrete a digesting enzyme known as pepsin, which has the potential to weaken the mucous layer that normally coats the stomach when produced in excess

More promising, perhaps, are multi-target approaches that simultaneously enhance EAAT2 function and reduce oxidative stress, potentially offering a more robust neuroprotective effect [403]

Benign Prostatic Hyperplasia (BPH), or prostate enlargement, affects millions of men as they age

Deficiencies in other micronutrients, including vitamin B 6 , vitamin B 12 , and omega-3 fatty acids, have been linked to depression, and vitamin D deficiency has also been associated with negative effects on mood (51, 144)