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The overwhelming ERS results in tubular cell injury and ultimately contributes to the progression of kidney damage (79)

Mira Meeus, Jo Nijs, Linda Hermans, Dorien Goubert & Patrick Calders (2013) The role of mitochondrial dysfunctions due to oxidative and nitrosative stress in the chronic pain or chronic fatigue syndromes and fibromyalgia patients: peripheral and central mechanisms as therapeutic targets?, Expert Opinion on Therapeutic Targets, 17:9, 1081-1089, DOI: 10.1517/14728222.2013.818657 Myhill S, Booth NE, McLaren-Howard J

A bacterial pathogen induces developmental slowing by high reactive oxygen species and mitochondrial dysfunction in Caenorhabditis elegans

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The investigation revealed that under 500 M aluminum chloride (AlCl 3 ) stress caused significant cellular lysis of root tissues