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A healthier gut microbiome may support mood stability and better adherence to treatment over time

149 By promoting neurotransmitter release, facilitating vesicle docking, and upregulating the expression of synaptic vesicle proteins, BDNF, which is released by astrocytes in response to long-term antidepressant therapy, may assist in increasing synaptic plasticity at presynaptic terminals

Patients should contact their GP if they experience persistent vomiting, severe abdominal pain, signs of dehydration, or symptoms of hypoglycaemia

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