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The clinical trials that showed disappointing results used oral administration

Immunostimulatory potential of extracellular vesicles isolated from an edible plant, Petasites japonicus , via the induction of Murine dendritic cell maturation

While mutations in the drug target are involved in the resistance to many molecularly targeted agents [164], mutations in IGF-IR are barely detected in cancer cells resistant to anti-IGF-IR agents

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