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The goal is safe, sustainable progress that supports metabolic health, lean muscle preservation and long-term results

Zepbound affects two receptors, the GLP-1 and GIP, whereas Wegovy only affects the GLP-1 receptor, says Mir Ali, MD, a bariatric surgeon and medical director of MemorialCare Surgical Weight Loss Center at Orange Coast Medical Center in Fountain Valley, California

For individuals without insurance, there may be assistance programs available to help qualifying individuals access semaglutide medications at reduced costs

For mild itching or discomfort , over-the-counter non-drowsy antihistamines (such as cetirizine or loratadine) may provide relief, particularly if symptoms suggest an allergic component

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