does nadph reduce glutathione NADPH—The Forgotten Reducing Equivalent Glutathione Pathways

113 This finding provides potentially fresh insights into pathology and metabolic regulation, but more study about the NNT reversal process in cancer is urgently needed

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Progress in Retinal and Eye Research, 2003

While the greater amount of cellular reduced GSH is found in the cytosol and mitochondria, the endoplasmic reticulum becomes a reservoir of small concentrations of the oxidized form of GSH (GSSG)

A lower pool of this antioxidant may lead to more oxidative damage in the skin and can contribute to dullness or uneven tone