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The GLP-1 receptor activation enhances insulin secretion and reduces appetite

This led to the first approved GLP-1 receptor agonist, exenatide (Byetta), in 2005 which binds to the same receptor but works far longer

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[DOI] [PubMed] [Google Scholar] [181].Casey PG, Gardiner GE, Casey G, Bradshaw B, Lawlor PG, Lynch PB, et al

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