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This translocation is supported by Karyopherin 1 (importin 5), that functions as an adaptor molecule, and Karyopherin 1 (importin 1), the transport receptor that allows NRF2 translocation from the cytoplasm to the nuclear side of the NPC, due to Nuclear Localization Signal (NLS) sequences in NRF2 [160]

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Older adults face increased risks including gastrointestinal side effects leading to dehydration, accelerated muscle loss (sarcopenia), drug interactions with multiple medications, and hypoglycaemia risk if taking diabetes medications

Cover sits in a similar space but the wording varies by insurer