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[DOI] [PMC free article] [PubMed] [Google Scholar] [92].He M, Cheng KF, VanPatten S

It helps when baseline signaling is below the optimal range, but can worsen anxiety when norepinephrine is already excessive

Psychological Dependence While peptides themselves are not inherently addictive, their misuse can lead to psychological dependence or a perceived need for continued use