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It is a high affinity melanocortin receptor agonist (Ki values are 0.67, 6.6, 34 and 46 nM for MC1, MC4, MC3 and MC5 receptors respectively)

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Next, we established a peptide-exchange protocol for HLA-C*04:01 and screened a small peptide library to identify novel, functional ligands for the activating receptor KIR2DS4