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In high fat diet (HFD) and streptozotocin (STZ)-induced type 2 diabetic mice model and HK-2 cells, after treatment with metformin (200 mg/kg/d) for 24 weeks, some indicators of mitophagy (LC3II, Pink1, Parkin, Atg5) were examined

Rapid Oxidation: Free glutathione quickly oxidizes into glutathione disulfide (GSSG) upon exposure to air or light, losing its efficacy and causing discoloration (browning) of the product

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(2016, 2019) reported significant improvements in UPDRS total scores and DAT binding in caudate and putamen in the NAC, with a mean decrease of 3.25 points ( P = 0.004) (Monti et al