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The medication is intentionally introduced slowly to reduce side effects, and appetite suppression often becomes more noticeable after dose increases
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Further studies include REDEFINE 3 (heart benefits vs placebo in adults with heart disease) and REDEFINE 4 (84-week head-to-head vs tirzepatide 15 mg)
This metabolic shift can produce ketone bodies , which are released through breath, urine, and sweat, potentially creating a distinctive odour that some describe as fruity or acetone-like
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