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Type 2 diabetes In type 2 diabetes, metformin therapy is associated with B12 deficiency, resulting in a 10% higher risk of developing B12 depletion

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doi: 10.1016/j.jcjd.2019.05.008 104 Sanchez-RangelE.InzucchiS

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In research settings, NAD+ is widely studied for its involvement in oxidative metabolism, sirtuin pathway activation, DNA repair pathways, cellular stress models, and metabolic-signaling systems

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