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For the gut specifically, that translates into support for the gut lining and surrounding tissue

Evidence of prior or ongoing hepatocellular damage, such as apoptosis/necrosis, chronic inflammation, chronic congestion, fibrosis, cirrhosis, or a known cause of toxicity

Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation