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The results showed that the overexpression of ATP6AP1L gene with pcDNA3.1-GST DAF -ATP6AP1L and pcDNA3.1-GST CEAM7 -ATP6AP1L could significantly inhibit the proliferation of K-562 cells compared with the control cells transfected with empty vectors, pcDNA3.1-GST DAF, and pcDNA3.1-GST CEAM7 , respectively

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Hence, it leads to skin whitening, even skin tone, and reduced dark spots

Results from clinical trials suggest that such drugs could have potential for the treatment of asthma, which is one of the most chronic inflammatory pulmonary diseases in the world and often linked to both type 2 diabetes and obesity (Wu, Stokes Peebles)