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With consistent use, this leads to gradual and sustainable weight loss

47 While lifestyle modifications, regular physical activity and diet are recommended for all HF patients, weight reduction should be a direct therapy goal for patients with HFpEF and obesity

There are three categories of VKDB depending on the age of onset: early (0-24 hours), classic (1-7 days), and late (2 to 12 weeks and up to 6 months of age) (123, 125-127)

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