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As an example of such a multipronged approach, the Neotone formulation simultaneously targeting melanocytes, fibroblasts, and endothelial cells with the combination of five actives (niacinamide, licorice extract, diacetylboldine, a DKK1 agonist, and an inhibitor of EDN-1 synthesis) was found to be as effective as hydroquinone 4% cream in the management of facial melasma, while inducing fewer side effects [214]

It can be used for combating heart disease, liver disease, alcohol use disorder, and even aging

Anschutz-affiliated providers at the CU Health and Wellness Center offer academic obesity medicine with access to clinical research and multidisciplinary teams

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