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Inclusion criteria included being: (a) a current alcohol drinker

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fMRI data (10 min pre-infusion baseline, 10 min during bolus infusion, and twice 10 min during infusion) were acquired as T2*-weighted gradient echo echo-planar (EPI) images, 43 axial slices with an interleaved slice order covering the whole brain including brain stem, TR = 2.8 s, TE = 30 ms, flip angle = 90, 110 110 matrix, field of view = 192 192 mm and voxel size = 3 3 3 mm

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Metabolic improvements including better blood sugar, lower blood pressure, and cholesterol