Versus retinol and retinoic acid (cosmetic anti-ageing reference): retinol acts via RAR/RXR receptors and transcriptional modulation but with irritating effects (desquamation, solar sensitivity)
It helps to fade dark spots, hyperpigmentation, and other discolorations caused by acne scars or sun exposure
As the bodys master antioxidant, glutathione recycles other antioxidants and helps repair cellular damage caused by daily exposures to environmental toxins and free radicals caused by chronic infections
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A large Cochrane review noted that many of the positive studies had methodological limitations, and not all trials found significant benefits. It's also worth knowing that some prominent DHEA researchers have disclosed commercial interests in DHEA supplementation, which is important context when weighing the evidence