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In males, spontaneous erections 1-5 hours after administration (priapism), associated with yawning and stretching complex

This makes retatrutide a GLP-1/GIP/glucagon triple agonist, and the first molecule of its kind to reach advanced clinical trials

Bone turnover markers showed that P-CTX increased by 27% after the low-calorie diet and decreased in all groups by week 26, with the lowest levels in the placebo group