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doi:10.1001/jama.2018.13022 Apovian CM, Aronne LJ, Bessesen DH, et al

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The expression of GIP receptors in vascular adipose tissue in endothelial cells and monocytes/macrophages probably influence each other and increase inflammation [16]

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Patient-specific factors also play a roleindividuals with pre-existing GERD, those taking higher doses, and patients with delayed baseline gastric emptying may experience more pronounced symptoms