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References Noctor G, Mhamdi A, Chaouch S, Han Y, Neukermans J, Marquez-Garcia B, Queval G, Foyer CH

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FOXO4-DRI is studied in preclinical longevity models to evaluate how senescent cell clearance influences biological aging markers

Methods Patient cohort CSF (ventricular and/or lumbar) and plasma samples were collected from 109 patients evaluated for suspected normal pressure hydrocephalus (NPH) at the Brown University Health NPH Multidisciplinary Clinic between January 2020 and April 2025 ( Figure 1B , Figure 5A and Table 1 )