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However, long-term NNMT inhibition in humans hasn't been characterized beyond small pilot cohorts, so concerns about sustained NAD+ elevation (which could theoretically promote certain cancers via PARP or SIRT activation) remain speculative but unresolved
However, it may take a number of days or weeks before a person notices improvements in their symptoms
They govern hormone release, immune activity, cellular repair, appetite regulation, and dozens of other physiological processes
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