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Research indicates that GLP-1 receptors are highly concentrated in the mesolimbic reward system the brains hub for dopamine and impulsivity ( PMC , 2025)

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Thus, in HUVECs, Mg 2+ deficiency promotes oxidative stress, and the upregulation of TXNIP seems to participate in the accumulation of ROS, triglycerides in lipid droplets, and hyperpermeability [202]

While existing systematic reviews and retrospective cohorts have not identified stable, potent teratogenic signals, the heterogeneity in exposure windows, drug types/dosages, and baseline metabolic riskscompounded by residual confoundingrenders any safe vs