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After verifying oxidizing influences on Mia40 in vivo , we next wanted to test which reducing pathways act on Mia40 or more specifically whether the redox state of Mia40 is susceptible to changes in E GSH (Figure 8A)

However, it should be noted that no human experimentation has been conducted thus far

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[Overstreet JW

The critical aggregation concentrations (CAC) of these compounds were determined to be below 0.3 mM (Fig