glp 1 gip and glucagon New strategies for the treatment of obesity metabolic dysfunctions Effects of site-directed mutagenesis of

Public dataset and bioinformatics The GEO datasets were downloaded from NCBI (www.ncbi.nlm.nih.gov)

The analysis of 16 s RNA microbial community diversity demonstrated that the predominant phyla were Firmicutes, Bacteroidetes, Proteobacteria, and Actinobacteria

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Secondary outcomes Secondary outcomes include changes in exhaled CO levels and smoking cessation rate at weeks 12 and 24