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RM-718, PL7737 and 710GO all report efficacy with acceptable nonclinical safety profiles, including no evidence of cardiac activation (25, 130)

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Some targeted antioxidant supplementation has shown positive results, like vitamin D and Omega-3 Fatty Acids (OFAs), which have been promising in reducing inflammation and OS in HTN/DM when deficiency is confirmed (Mazidi et al., 2020)

We aimed to explore flexible management of GLP-1RA therapy when tolerability issues arise, including gastrointestinal (GI) adverse events (AEs), as a potentially important part of overcoming barriers to treatment persistence

3 Empagliflozin (Jardiance) and liraglutide (Victoza) have been shown to reduce cardiovascular and all-cause mortality when added to standard care