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Opposite effects of dexamethasone on serum concentrations of 3,3,5-triiodothyronine (reverse T3) and 3,35-triiodothyronine (T3)

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World J Gastroenterol

For one or two months out of every three they are too exhausted to function

In contrast, M-CuP showed negligible binding to either target, with maximal responses below 5 response units (RU) across all tested concentrations, confirming the essential role of multivalent architecture in cooperative target engagement