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In this setting, product choice should be conservative: clear labeling, veterinary compatibility, and avoidance of aggressive detox claims

Key proposed pathways include: Opioid system interaction: DSIP has been reported to interact with opioid receptors in animal studies, which may partly explain observations about pain modulation and sleep promotion

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In topical skincare, these peptides are well-studied and are common in serums and creams that support collagen production, improve skin texture, and reduce ageing signs

Other risk factors for the condition include gastric surgery, which can disrupt the production of intrinsic factors, which the body needs to take up B12