For instance, the NBC contains more bound bile acids and bound bile pigments, which may be one of the reasons for its better efficacy (Xu et al., 2017)
This binding triggers a cascade of effects: delayed gastric emptying, reduced glucagon secretion, enhanced insulin sensitivity, and most importantly for weight loss, decreased food intake through central appetite suppression (Wilding et al., NEJM, 2021)
It has strong hygroscopicity and is suitable for liquid preparations
This is the safest point to begin to assess tolerance and minimize the risk of side effects
Invest Ophthalmol Vis Sci 55(12):81739 Thaller M et al (2023) The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes