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Treatment of cockroach allergen asthma model with imatinib attenuates airway responses

To reinforce these data, we also performed immunostainings for Iba1 (macrophages), CD68 (TAMs), FOXP3, CD4 and CD8 (TILs), as well as double immunostainings for FOXP3 and CD4 (Tregs) in lung sections from LLC-challenged mice

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These are among the largest weight-loss figures reported for any pharmacological agent in a Phase 2 obesity trial

"Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism, and reduces diastolic blood pressure." Journal of Clinical Endocrinology & Metabolism 82.3 (1997): 727-734