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164 In addition, hyperglycemia and other metabolic disorders such as dyslipidemia, inflammatory factors, excess IAPP and alterations in the gut microbiota, combine to contribute to IR and/or cell dysfunction through the common pathways of inflammation, ERS and oxidative stress (Fig

Thus, increased Nrf2 activity does not initiate cancer development but confers advantages in terms of proliferation and stress resistance once a cell acquires uncontrolled proliferative properties

Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others References Kirchmair J, Gller AH, Lang D et al (2015) Predicting drug metabolism: experiment and/or computation

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