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Cochrane handbook for systematic reviews of interventions 5.1.0 (2011)

6-Aminonicotinamide reduces PQ-induced death of SKN-SH cells by inhibiting the PPP pathway through its action on 6-phosphogluconate dehydrogenase production and G6PD [122]

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A: Observational research suggests that people taking GLP-1 receptor agonists may have a lower risk of developing substance use disorders, but clinical trials are needed to confirm whether these drugs directly influence addiction

Prescribing of any treatment follows the National Institute for Health and Care Excellence (NICE) guidelines as well as other leading national best practice guidelines