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Improved Health-Related Quality of Life (HRQoL): Studies like SURMOUNT-2 (published March 2025) have shown that Tirzepatide treatment is associated with significantly improved self-reported HRQoL, encompassing both physical and psychosocial aspects of functioning

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Sleep Regulation Improved sleep duration, quality, and REM in chronic insomniacs

( PLOS ONE 9 :e104176, 2014) For the the second questionWhy do individuals with narcolepsy weigh more than healthy control subjects?Cizza hypothesized that individuals with narcolepsy have decreased energy expenditure compared with healthy control subjects