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In human serum assays, native IGF-1 circulates almost entirely bound while IGF-1 LR3 shows minimal binding

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Potential Benefits (Reported in Research Settings) Although not FDA-approved for clinical use, animal and cellular studies suggest IGF-1 LR3 may have: Increased Muscle Fiber Growth By enhancing both hypertrophy (size) and hyperplasia (number of muscle fibers)

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