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Nrf2 is important for cell cycle regulation and its deficiency is manifested as G2/M-phase arrest (Reddy et al

No se requiere monitorizacin de enzimas pancreticas de rutina en ausencia de sntomas

Why this study is important This is the first headtohead randomized comparison of a dual GIP/GLP1 agonist vs a selective GLP1 RA on kidney outcomes

Nevertheless, the concept is fascinating because it shifts the discussion from which receptor we activate to where we want the biological effect to occur

Despite this breakthrough, the cross-sectional nature of such studies limits causal inference and validation of biomarker specificity