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Furthermore, as a non-standardized intervention, it allows for personalized implementation tailored to individual patient needs

TRPV1 is also activated by capsaicin (hot peppers), low extracellular pH, and noxious heat.[ref] TRPA1 is activated by VOCs, cigarette smoke, heavy metals, naphthalene (moth balls), formaldehyde, and styrene.[ref] TRP receptors are highly expressed in the olfactory and trigeminal nerve endings and in the brain

Clinically, it behaves similarly to oral spray with somewhat different mechanics

PubMed Veronese N, Stubbs B, Solmi M, Ajnakina O, Carvalho AF, Maggi S

second as a template for RNA replication