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6 Discussion This review has summarized the multiple mechanisms by which IF affects fatty acid metabolic reprogramming and the neuroimmune microenvironment, and explored its potential applications in neurodegenerative, autoimmune, and neurotraumatic diseases

Cell Signalling 4668S

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In contrast, depression is typically characterized by reduced neuroplasticity, including hippocampal atrophy, decreased dendritic spine density, and impaired neurogenesis (Doherty et al., 2019)